故事讲述宇航员任务期间突发意外，伤病严重无法支撑返回地球治疗。情急之下，一名女外科医生临危受命，亲身飞赴空间站展开救援行动。时间有限，巨大的困难与挑战下，一场零重力下的极限救援即将上演！
　　影片为人类首部太空实拍电影。

　　After serving two years on a military outpost in the middle of an ocean – four soldiers are waiting for a new crew to replace them. When the long-awaited boat finally appears, it’s empty with no relief on board. When trying to find out what happened to the boat and the missing crew, they realize they’ve lost all communications with home. Cut off from the rest of the world and no one coming to get them, Baines, Sullivan, Cassidy and Hendryx must fight with suspicions about each other and find a new way to get home. If home still exists.