本季将去到拉斯维加斯，继续为人们“换新”生活，从一个找不到自信的前演出女孩到一个专心工作、需要一些变化的图书管理员。

　　The Fab Five return to New Orleans to jazz up the lives of their heroes - one emotional makeover at a time. From a coach and teacher to Deaf students struggling to realize his value, to a Bayou-born outdoorsman looking to reignite the spark in his marriage, expect more laughter and tears as Queer Eye continues to transform lives and celebrate the power of kindness.

　　John Mulaney returns to his Chicago high school with David Letterman as they candidly discuss addiction, fatherhood and the state of stand-up comedy.